Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464039 | 1.00 | TRPV1 (0.41) | TRPV1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6457292 | 0.92 | TTR (0.38) | KMT2AMEN1MAPTSRD5A1TDP1 | |
| SCHEMBL6457287 | 0.92 | TTR (0.38) | KMT2AMEN1MAPTSRD5A1TDP1 | |
| SCHEMBL6455921 | 0.91 | TDP1 (0.41) | TRPV1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL6452092 | 0.91 | ALDH1A1 (0.40) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6455915 | 0.91 | TDP1 (0.41) | TRPV1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL6452087 | 0.91 | ALDH1A1 (0.40) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6454150 | 0.91 | GRIN1 (0.37) | TRPV1SMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL6454153 | 0.91 | GRIN1 (0.37) | TRPV1SMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL6453527 | 0.89 | EPHX2 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |