⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxazole SCHEMBL29728171 | 0.96 | — | — | |
| Oxazole SCHEMBL14 | 0.96 | — | — | |
| Oxazole SCHEMBL1743576 | 0.96 | — | — | |
| Oxazole SCHEMBL7538737 | 0.93 | — | — | |
| Oxazole SCHEMBL9452923 | 0.93 | — | — | |
| Oxazole SCHEMBL1128503 | 0.93 | — | — | |
| Oxazole SCHEMBL983076 | 0.93 | — | — | |
| Oxazole SCHEMBL5199619 | 0.93 | — | — | |
| Oxazole SCHEMBL3864385 | 0.93 | — | — | |
| Oxazole SCHEMBL986132 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501699-B2 | Bicyclic nucleosides and nucleotides as therapeutic agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-08-06 | — | — | US | disclosed |
| US-8415309-B2 | Bicyclic nucleosides and nucleotides as therapeutic agents | BIOTA SCIENTIFIC MANAGMENT PTY LTD (AT) | 2013-04-09 | — | — | US | disclosed |
| US-20130018013-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-01-17 | — | — | US | disclosed |
| US-20120122811-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-05-17 | — | — | US | disclosed |
| US-8119607-B2 | Bicyclic nucleosides and nucleotides as therapeutic agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-02-21 | — | — | US | disclosed |
| EP-2313102-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | Biota Scientific Management (AU) | 2011-04-27 | — | — | EP | disclosed |
| US-20100035836-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-02-11 | — | — | US | disclosed |
| WO-2010002877-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-01-07 | — | — | WO | disclosed |
| US-20090163563-A1 | Phorboxazole Compounds and Methods of Their Preparation | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-06-25 | — | — | US | disclosed |
| US-7485631-B2 | Phorboxazole compounds and methods of their preparation | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-02-03 | — | — | US | disclosed |
| US-20070021479-A1 | Phorboxazole compounds and methods of their preparation | UNIVERSITY OF PENNSYLVANIA | 2007-01-25 | — | — | US | disclosed |