Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452367 | 1.00 | TNK2 (0.38) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL6450932 | 0.97 | TNK2 (0.37) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL6450935 | 0.97 | TNK2 (0.37) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL7923264 | 0.96 | TNK2 (0.37) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL7923270 | 0.96 | TNK2 (0.37) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL6453274 | 0.96 | TNK2 (0.37) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL6453266 | 0.96 | TNK2 (0.37) | TNK2KDM1AGRM2S1PR1HRH3 | |
| SCHEMBL6454095 | 0.94 | TNK2 (0.39) | TNK2KDM1AGRM2HRH3DGAT1 | |
| SCHEMBL6454097 | 0.94 | TNK2 (0.39) | TNK2KDM1AGRM2HRH3DGAT1 | |
| SCHEMBL6450904 | 0.91 | TNK2 (0.36) | TNK2KDM1AGRM2DGAT1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |