Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454095 | 1.00 | TNK2 (0.39) | TNK2KDM1ACYP2C9GRM2ALDH1A1 | |
| SCHEMBL6452363 | 0.94 | TNK2 (0.38) | TNK2KDM1AGRM2FAAHGRIN1 | |
| SCHEMBL6452367 | 0.94 | TNK2 (0.38) | TNK2KDM1AGRM2FAAHGRIN1 | |
| SCHEMBL6450935 | 0.93 | TNK2 (0.37) | TNK2KDM1AGRM2MAPTFAAH | |
| SCHEMBL6450932 | 0.93 | TNK2 (0.37) | TNK2KDM1AGRM2MAPTFAAH | |
| SCHEMBL6453274 | 0.92 | TNK2 (0.37) | TNK2KDM1AGRM2MAPTFAAH | |
| SCHEMBL7923270 | 0.92 | TNK2 (0.37) | TNK2KDM1AGRM2MAPTFAAH | |
| SCHEMBL7923264 | 0.92 | TNK2 (0.37) | TNK2KDM1AGRM2MAPTFAAH | |
| SCHEMBL6453266 | 0.92 | TNK2 (0.37) | TNK2KDM1AGRM2MAPTFAAH | |
| SCHEMBL6452257 | 0.92 | TNK2 (0.38) | TNK2KDM1AGRM2FAAHGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |