Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453266 | 1.00 | TNK2 (0.37) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL6453274 | 1.00 | TNK2 (0.37) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL7923270 | 1.00 | TNK2 (0.37) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL6450935 | 0.99 | TNK2 (0.37) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL6450932 | 0.99 | TNK2 (0.37) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL6452363 | 0.96 | TNK2 (0.38) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL6452367 | 0.96 | TNK2 (0.38) | TNK2MGLLKDM1AGRM2S1PR1 | |
| SCHEMBL6454095 | 0.92 | TNK2 (0.39) | TNK2KDM1AGRM2HRH3MAPT | |
| SCHEMBL6454097 | 0.92 | TNK2 (0.39) | TNK2KDM1AGRM2HRH3MAPT | |
| SCHEMBL6454877 | 0.91 | TNK2 (0.35) | TNK2MGLLKDM1AGRM2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |