Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452730 | 1.00 | HRH3 (0.34) | HRH3L3MBTL1HCRTR1HCRTR2TRPV1 | |
| SCHEMBL6454321 | 0.88 | L3MBTL1 (0.43) | HRH3L3MBTL1ESR2KDM1AMAOB | |
| SCHEMBL6454317 | 0.88 | L3MBTL1 (0.43) | HRH3L3MBTL1ESR2KDM1AMAOB | |
| SCHEMBL6461013 | 0.87 | FASN (0.36) | TRPV1CETP | |
| SCHEMBL6461009 | 0.87 | FASN (0.36) | TRPV1CETP | |
| SCHEMBL6462856 | 0.85 | — | — | |
| SCHEMBL6462854 | 0.85 | — | — | |
| SCHEMBL6458365 | 0.84 | TRPV1 (0.33) | HRH3L3MBTL1HCRTR1HCRTR2TRPV1 | |
| SCHEMBL6458359 | 0.84 | TRPV1 (0.33) | HRH3L3MBTL1HCRTR1HCRTR2TRPV1 | |
| SCHEMBL6457405 | 0.84 | KDM1A (0.32) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |