Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461009 | 1.00 | FASN (0.36) | FASNSCN9AGRM2APPCYP3A4 | |
| SCHEMBL6453917 | 0.90 | GRM2 (0.41) | FASNGRM2APPCYP3A4CYP2C9 | |
| SCHEMBL6453913 | 0.90 | GRM2 (0.41) | FASNGRM2APPCYP3A4CYP2C9 | |
| SCHEMBL6452519 | 0.88 | FASN (0.33) | FASNAPPCYP3A4CYP2C9 | |
| SCHEMBL6452523 | 0.88 | FASN (0.33) | FASNAPPCYP3A4CYP2C9 | |
| SCHEMBL6453790 | 0.87 | SCN9A (0.36) | FASNSCN9AGRM2APPCYP3A4 | |
| SCHEMBL6453787 | 0.87 | SCN9A (0.36) | FASNSCN9AGRM2APPCYP3A4 | |
| SCHEMBL6452735 | 0.87 | HRH3 (0.34) | CETPTRPV1 | |
| SCHEMBL6452730 | 0.87 | HRH3 (0.34) | CETPTRPV1 | |
| SCHEMBL6456899 | 0.86 | FASN (0.37) | FASNGRM2APPCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |