Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452782 | 1.00 | EPHX2 (0.35) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL6452788 | 1.00 | EPHX2 (0.35) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL5687253 | 0.95 | EPHX2 (0.33) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL5687258 | 0.95 | EPHX2 (0.33) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL6453170 | 0.87 | EPHX2 (0.39) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL6453175 | 0.87 | EPHX2 (0.39) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL6453371 | 0.86 | EPHX2 (0.36) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL6453367 | 0.86 | EPHX2 (0.36) | EPHX2KDM1ARCOR1HRH3MEN1 | |
| SCHEMBL6455247 | 0.86 | DRD2 (0.36) | KDM1ASLC6A4SLC6A3 | |
| SCHEMBL6455248 | 0.86 | DRD2 (0.36) | KDM1ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |