Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453367 | 1.00 | EPHX2 (0.36) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL5683503 | 0.94 | EPHX2 (0.34) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL5683511 | 0.94 | EPHX2 (0.34) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL13433664 | 0.90 | L3MBTL1 (0.37) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL6453175 | 0.89 | EPHX2 (0.39) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL6453170 | 0.89 | EPHX2 (0.39) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL6452788 | 0.86 | EPHX2 (0.35) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL6452777 | 0.86 | EPHX2 (0.35) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL6452782 | 0.86 | EPHX2 (0.35) | EPHX2L3MBTL1KDM1AHRH3RCOR1 | |
| SCHEMBL6451784 | 0.84 | CYP2C9 (0.42) | EPHX2L3MBTL1KDM1AHRH3RCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |