Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452974 | 1.00 | DRD2 (0.40) | DRD2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6454214 | 0.93 | DRD2 (0.38) | DRD2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6454211 | 0.93 | DRD2 (0.38) | DRD2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6454759 | 0.92 | DRD2 (0.45) | DRD2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6451902 | 0.92 | DRD2 (0.45) | DRD2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6451898 | 0.92 | DRD2 (0.45) | DRD2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6462363 | 0.91 | KCNH2 (0.38) | DRD2CYP2C9SLC6A3MEN1KMT2A | |
| SCHEMBL6462364 | 0.91 | KCNH2 (0.38) | DRD2CYP2C9SLC6A3MEN1KMT2A | |
| SCHEMBL6451682 | 0.90 | KCNH2 (0.40) | DRD2MAPTSLC6A3KCNH2 | |
| SCHEMBL6451686 | 0.90 | KCNH2 (0.40) | DRD2MAPTSLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |