⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789604 | 0.74 | — | — | |
| SCHEMBL6443242 | 0.74 | — | — | |
| SCHEMBL65952 | 0.69 | — | — | |
| SCHEMBL11400539 | 0.69 | — | — | |
| SCHEMBL3149038 | 0.69 | HMBS (0.43) | — | |
| SCHEMBL8619374 | 0.66 | — | — | |
| SCHEMBL6561706 | 0.66 | — | — | |
| SCHEMBL8208273 | 0.66 | HMBS (0.92) | — | |
| SCHEMBL11401624 | 0.62 | — | — | |
| SCHEMBL2912200 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045517-B2 | Glycosylated aminocoumarins and methods of preparing and uses of same | UNIVERSITY COLLEGE LONDON (GB) | 2015-06-02 | — | — | US | disclosed |
| EP-2627661-B1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | UNIV LONDON (GB) | 2015-03-18 | — | — | EP | disclosed |
| US-20130274213-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | UNIVERSITY COLLEGE LONDON (GB) | 2013-10-17 | — | — | US | disclosed |
| EP-2627661-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | University College London (GB) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012049521-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2012-04-19 | — | — | WO | disclosed |
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0032048-A1 | Pyrroloylpyrrole derivatives, processes for their preparation and their use | BEECHAM GROUP PLC (GB) | 1981-07-15 | — | — | EP | disclosed |