Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CTSD | P07339 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208462 | 0.85 | ALDH1A1 (0.83) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL15997924 | 0.83 | ALDH1A1 (0.80) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL2062424 | 0.83 | ALDH1A1 (0.78) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL2650229 | 0.82 | POLB (0.72) | ALDH1A1POLBSMN1; SMN2GAAKDM4E | |
| SCHEMBL6449628 | 0.82 | ALDH1A1 (0.83) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL1208576 | 0.82 | ALDH1A1 (0.83) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL1207177 | 0.81 | ALDH1A1 (0.76) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL1207037 | 0.81 | ALDH1A1 (0.76) | ALDH1A1POLBTDP1ALPLSMN1; SMN2 | |
| SCHEMBL5181163 | 0.81 | KMT2A (0.76) | ALDH1A1POLBTDP1GAAHTT | |
| SCHEMBL1963164 | 0.81 | KMT2A (0.65) | ALDH1A1POLBCTSDHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | ALDH1A1 287/4885POLB 2806/4885TDP1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.