Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453207 | 1.00 | SIGMAR1 (0.33) | SIGMAR1LSSTEAD1HTR2CGAA | |
| SCHEMBL6457872 | 0.97 | GAA (0.34) | SIGMAR1LSSTEAD1HTR2CGAA | |
| SCHEMBL6457875 | 0.97 | GAA (0.34) | SIGMAR1LSSTEAD1HTR2CGAA | |
| SCHEMBL6461151 | 0.96 | GAA (0.36) | SIGMAR1LSSGAAMAPTP2RY14 | |
| SCHEMBL6454050 | 0.96 | GAA (0.36) | SIGMAR1LSSGAAMAPTP2RY14 | |
| SCHEMBL6454054 | 0.96 | GAA (0.36) | SIGMAR1LSSGAAMAPTP2RY14 | |
| SCHEMBL6461154 | 0.96 | GAA (0.36) | SIGMAR1LSSGAAMAPTP2RY14 | |
| SCHEMBL6457327 | 0.94 | ALDH1A1 (0.34) | SIGMAR1TEAD1HTR2CMAPTCNR1 | |
| SCHEMBL6457320 | 0.94 | ALDH1A1 (0.34) | SIGMAR1TEAD1HTR2CMAPTCNR1 | |
| SCHEMBL18385887 | 0.91 | HTR2C (0.36) | LSSHTR2CGAAMAPTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |