Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 9/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453257 | 1.00 | RAB9A (0.35) | RAB9AGAAMEN1MAPK1KMT2A | |
| SCHEMBL6453867 | 0.97 | RAB9A (0.34) | RAB9AGAAMEN1MAPK1KMT2A | |
| SCHEMBL6453872 | 0.97 | RAB9A (0.34) | RAB9AGAAMEN1MAPK1KMT2A | |
| SCHEMBL6457968 | 0.96 | GAA (0.36) | RAB9AGAACYP2C9EPHX2CNR2 | |
| SCHEMBL6450944 | 0.96 | GAA (0.36) | RAB9AGAACYP2C9EPHX2CNR2 | |
| SCHEMBL6450953 | 0.96 | GAA (0.36) | RAB9AGAACYP2C9EPHX2CNR2 | |
| SCHEMBL6457970 | 0.96 | GAA (0.36) | RAB9AGAACYP2C9EPHX2CNR2 | |
| SCHEMBL6452998 | 0.94 | CYP2C9 (0.38) | RAB9AMEN1MAPK1KMT2ACYP2C9 | |
| SCHEMBL6453009 | 0.94 | CYP2C9 (0.38) | RAB9AMEN1MAPK1KMT2ACYP2C9 | |
| SCHEMBL6454956 | 0.90 | L3MBTL1 (0.38) | RAB9ACYP2C9EPHX2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |