SCHEMBL6453423

SCHEMBL6453423

C=CCC[C@@H]1CC[C@@H]2CC(c3ccc(CC)c(F)c3)CC[C@@H]2C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.32
CTSC P53634 3/20 0.31
CTSK P43235 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6453427 1.00 HRH3 (0.32) HRH3CTSCCTSK
SCHEMBL6456891 0.91
SCHEMBL6456887 0.91
SCHEMBL6456084 0.90 HTR2A (0.31)
SCHEMBL6456081 0.90 HTR2A (0.31)
SCHEMBL6458356 0.87 CCR2 (0.34)
SCHEMBL6458361 0.87 CCR2 (0.34)
SCHEMBL6455571 0.86 SLC6A3 (0.31)
SCHEMBL6455567 0.86 SLC6A3 (0.31)
SCHEMBL6452192 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed