Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.30 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17836052 | 0.97 | — | — | |
| SCHEMBL6439666 | 0.86 | MAPT (0.32) | HPGD | |
| SCHEMBL6438161 | 0.83 | POLB (0.33) | — | |
| SCHEMBL8216444 | 0.82 | ESR1 (0.30) | — | |
| SCHEMBL6440175 | 0.81 | RAB9A (0.39) | TSHR | |
| SCHEMBL6438270 | 0.76 | MAPT (0.41) | HPGD | |
| SCHEMBL6438664 | 0.76 | MEN1 (0.39) | HPGDTSHR | |
| SCHEMBL6444339 | 0.73 | SOAT1 (0.32) | HPGDTSHR | |
| Hydrochloric Acid SCHEMBL8722331 | 0.73 | MEN1 (0.37) | HPGDTSHR | |
| Hydrochloric Acid SCHEMBL8722324 | 0.73 | MEN1 (0.37) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884857-B1 | Olefin polymerization process using supported constrained geometry catalysts | THE DOW CHEMICAL COMPANY (US) | 2005-04-26 | — | — | US | disclosed |
| US-6858557-B1 | Supported constrained geometry olefin polymerization catalysts | THE DOW CHEMICAL COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| US-6806326-B2 | TITANIUM COMPLEXES WITH DELOCALIZED PI-BONDED CYCLOPENTADIENYL MOIETY, AND COCATALYST; FOR EXAMPLE, 1-(TERT-BUTYLAMIDO)-2-(TETRAMETHYLCYCLOPENTADIENYL)-ETHANEDIYL TITANIUM DICHLORIDE AND METHYL ALUMOXANE | THE DOW CHEMICAL COMPANY | 2004-10-19 | — | — | US | disclosed |
| US-6686488-B2 | USING COORDINATION POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2004-02-03 | — | — | US | disclosed |
| US-6670432-B1 | Metal is bound to a delocalized substituted pi-bonded moiety (cyclopentadiene) to induce a constrained geometry about the metal; ethylene-styrene copolymer | THE DOW CHEMICAL COMPANY | 2003-12-30 | — | — | US | disclosed |
| US-20030065203-A1 | Constrained geometry addition polymerization catalysts | WILSON DAVID R (US) | 2003-04-03 | — | — | US | disclosed |
| US-20020128403-A1 | Constrained geometry addition polymerization catalysts | STEVENS JAMES C (US) | 2002-09-12 | — | — | US | disclosed |
| US-6075077-A | ETHYLENE COPOLYMER PREPARED USING A CYCLOPENTADIENE COORDINATION COMPLEX OF GIVEN FORMULA WHERE METAL IS BOUND TO A DELOCALIZED SUBSTITUTED PI-BONDED MOIETY TO INDUCE A CONSTRAINED GEOMETRY ABOUT THE METAL, AND COCATALYST | THE DOW CHEMICAL COMPANY (US) | 2000-06-13 | — | — | US | disclosed |
| US-6013819-A | AS POLYMERIZATION CATALYSTS FOR PRODUCING ADDITION POLYMERS | THE DOW CHEMICAL COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-5703187-A | ETHYLENICALLY UNSATURATED ADDITION POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0416815-B1 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | DOW CHEMICAL CO (US) | 1997-08-13 | — | — | EP | disclosed |
| EP-0774468-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |
| EP-0765888-A2 | Polymers obtainable with a constrained geometry addition polymerization catalyst and process of making atactic alpha-olefin polymers with such catalysts | THE DOW CHEMICAL COMPANY (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0764654-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0764664-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0764653-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0416815-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065203-A1 | Constrained geometry addition polymerization catalysts | CPSF6, CPSF1, PICALM | HPGD 1491/4885TSHR 4832/4885LOX 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.