Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453460 | 1.00 | GRIN1 (0.32) | GRIN1GRIN2BKDM1APDE4BGRM2 | |
| SCHEMBL6456142 | 0.92 | PDE4B (0.30) | KDM1APDE4BGRM2 | |
| SCHEMBL6456144 | 0.92 | PDE4B (0.30) | KDM1APDE4BGRM2 | |
| SCHEMBL6455847 | 0.90 | MGLL (0.31) | — | |
| SCHEMBL6455848 | 0.90 | MGLL (0.31) | — | |
| SCHEMBL6462244 | 0.89 | GRIN1 (0.33) | GRIN1GRIN2BKDM1APDE4BGRM2 | |
| SCHEMBL6462239 | 0.89 | GRIN1 (0.33) | GRIN1GRIN2BKDM1APDE4BGRM2 | |
| SCHEMBL6453559 | 0.89 | MGLL (0.31) | — | |
| SCHEMBL6453556 | 0.89 | MGLL (0.31) | — | |
| SCHEMBL6452539 | 0.89 | KDM1A (0.40) | GRIN1GRIN2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |