Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 15/20 | 0.65 |
| ▸ | AR | P10275 | 11/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148546 | 1.00 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL4665348 | 1.00 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL7148540 | 1.00 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8541351 | 0.91 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8538261 | 0.91 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8541353 | 0.91 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8540843 | 0.89 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8539739 | 0.89 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8768021 | 0.89 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8536196 | 0.89 | PGR (0.53) | PGRNR3C1ARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050064031-A1 | Combination contraceptive, kits that contain the latter, and a method that uses the latter | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050064031-A1 | Combination contraceptive, kits that contain the latter, and a method that uses the latter | GNRHR, PGRMC2, SHBG | PGR 5/4885NR3C1 120/4885AR 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.