Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454153 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6464036 | 0.91 | TRPV1 (0.41) | TRPV1MAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL6464039 | 0.91 | TRPV1 (0.41) | TRPV1MAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL6455059 | 0.90 | MAPT (0.32) | GRIN1GRIN2BTRPV1MAPTESR1 | |
| SCHEMBL6457292 | 0.90 | TTR (0.38) | GRIN1GRIN2BMAPTRAB9AESR1 | |
| SCHEMBL6457287 | 0.90 | TTR (0.38) | GRIN1GRIN2BMAPTRAB9AESR1 | |
| SCHEMBL6455056 | 0.90 | MAPT (0.32) | GRIN1GRIN2BTRPV1MAPTESR1 | |
| SCHEMBL6455915 | 0.89 | TDP1 (0.41) | GRIN1GRIN2BTRPV1MAPTGAA | |
| SCHEMBL6452092 | 0.89 | ALDH1A1 (0.40) | MAPTRAB9AGAASMN1; SMN2TDP1 | |
| SCHEMBL6452087 | 0.89 | ALDH1A1 (0.40) | MAPTRAB9AGAASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |