Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238277 | 0.92 | CHRM3 (0.52) | NTRK1CHRM3TDP1ALDH1A1KDM4E | |
| SCHEMBL10238274 | 0.90 | CHRM3 (0.50) | NTRK1CHRM3TDP1ALDH1A1KDM4E | |
| SCHEMBL4916882 | 0.90 | ATM (0.56) | NTRK1CHRM3ATMCYP1A2CYP2C9 | |
| SCHEMBL10238286 | 0.88 | CHRM3 (0.51) | NTRK1CHRM3ALDH1A1KDM4EMAPT | |
| SCHEMBL4915627 | 0.88 | ATM (0.43) | NTRK1CHRM3TDP1ALDH1A1KDM4E | |
| SCHEMBL4104692 | 0.86 | NTRK1 (0.52) | NTRK1CHRM3 | |
| SCHEMBL4094901 | 0.86 | TDP1 (0.58) | CHRM3TDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL10238279 | 0.83 | ATM (0.54) | NTRK1TDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL10238297 | 0.83 | ATM (0.50) | NTRK1TDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL646434 | 0.81 | CHRM3 (0.52) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20130190375-A1 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-20130190375-A1 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-7906656-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | NTRK1 775/4885CHRM3 346/4885TDP1 2029/4885 |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | Q6ZSR9, C1S, MRPL21 | NTRK1 1862/4885CHRM3 573/4885TDP1 1346/4885 |
| US-20130190375-A1 | CARBOXAMIDES | NAAA, CBR3, CNR1 | NTRK1 3426/4885CHRM3 1775/4885TDP1 2497/4885 |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | NTRK1 775/4885CHRM3 346/4885TDP1 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.