Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238297 | 0.90 | ATM (0.50) | TDP1ATMLMNAPOLBALDH1A1 | |
| SCHEMBL646511 | 0.89 | ATM (0.62) | TDP1SUCNR1CHRM3ATMF10 | |
| SCHEMBL10238274 | 0.89 | CHRM3 (0.50) | TDP1CHRM3ATMLMNAPOLB | |
| SCHEMBL10238277 | 0.88 | CHRM3 (0.52) | TDP1SUCNR1CHRM3ATMLMNA | |
| SCHEMBL10238279 | 0.88 | ATM (0.54) | TDP1ATMLMNAPOLBALDH1A1 | |
| SCHEMBL645443 | 0.86 | NTRK1 (0.46) | TDP1CHRM3ATMLMNAALDH1A1 | |
| SCHEMBL121957 | 0.85 | TDP1 (0.53) | TDP1SUCNR1CHRM3ATMF10 | |
| SCHEMBL29419144 | 0.85 | TDP1 (0.53) | TDP1SUCNR1CHRM3ATMF10 | |
| SCHEMBL14578046 | 0.85 | LMNA (0.68) | TDP1SUCNR1CHRM3ATMF10 | |
| SCHEMBL10238290 | 0.85 | NTRK1 (0.57) | CHRM3ATMLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | claimed |
| EP-1890540-A2 | CARBOXAMIDES | Bayer CropScience AG (DE) | 2008-02-27 | — | — | EP | claimed |
| WO-2006131221-A2 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | claimed |
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20130190375-A1 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-20130190375-A1 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-20130190375-A1 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-8431600-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2013-04-30 | — | — | US | disclosed |
| US-8431600-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2013-04-30 | — | — | US | disclosed |
| US-8431600-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2013-04-30 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1890540-A2 | CARBOXAMIDES | Bayer CropScience AG (DE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| WO-2006131221-A2 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105311-A1 | Carboxamides | NAAA, CBR3, CNR1 | TDP1 2497/4885SUCNR1 349/4885CHRM3 1775/4885 |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | Q6ZSR9, C1S, MRPL21 | TDP1 1346/4885SUCNR1 3884/4885CHRM3 573/4885 |
| US-20130190375-A1 | CARBOXAMIDES | NAAA, CBR3, CNR1 | TDP1 2497/4885SUCNR1 349/4885CHRM3 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.