Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL712074 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL9106678 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL9109508 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL13506304 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL1988852 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL2592019 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL6015091 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL1712572 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Dodecane SCHEMBL1267197 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 | |
| Heptane SCHEMBL1883478 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10FAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2024-03-14 | — | — | US | disclosed |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2022-02-24 | — | — | US | disclosed |
| CN-107412788-B | Novel compound for imaging Tau protein accumulated in brain | 国立研究开发法人量子科学技术研究开发机构 | 2021-06-18 | — | — | CN | disclosed |
| US-20200262829-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate in the Brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECH (JP) | 2020-08-20 | — | — | US | disclosed |
| US-10604516-B2 | Compounds for imaging tau proteins that accumulate in the brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2020-03-31 | — | — | US | disclosed |
| US-10494330-B2 | Methyl menthol derivative and cooling agent composition containing same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-12-03 | — | — | US | disclosed |
| EP-3275962-B1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2019-10-02 | — | — | EP | disclosed |
| US-20180057447-A1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2018-03-01 | — | — | US | disclosed |
| EP-3275962-A1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | Takasago International Corporation (JP) | 2018-01-31 | — | — | EP | disclosed |
| EP-2767532-B1 | NOVEL COMPOUND FOR IMAGING TAU PROTEIN ACCUMULATED IN THE BRAIN | NAT INST FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2015-08-27 | — | — | US | disclosed |
| CN-104736524-A | Novel compound for imaging Tau protein accumulated in brain | NAT INST RADIOLOG | 2015-06-24 | — | — | CN | disclosed |
| EP-2767532-A1 | NOVEL COMPOUND FOR IMAGING TAU PROTEIN ACCUMULATED IN THE BRAIN | National Institute of Radiological Sciences (JP) | 2014-08-20 | — | — | EP | disclosed |
| US-20050133371-A1 | Apparatus and method for Edman degradation on a microfluidic device utilizing an electroosmotic flow pump | WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | 2005-06-23 | — | — | US | disclosed |
| US-20040175822-A1 | Apparatus and method for edman degradation using a microfluidic system | WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | 2004-09-09 | — | — | US | disclosed |
| US-5798365-A | VIRICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | ALDH1A1 1880/4885LMNA 3874/4885HSD17B10 235/4885 |
| US-20180057447-A1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TRPM4, TAS2R41, TRPM2 | ALDH1A1 902/4885LMNA 3909/4885HSD17B10 2362/4885 |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | MAPT, FABP7, HTT | ALDH1A1 1691/4885LMNA 3929/4885HSD17B10 218/4885 |
| US-10494330-B2 | Methyl menthol derivative and cooling agent composition containing same | TRPM4, TAS2R41, TRPM2 | ALDH1A1 902/4885LMNA 3909/4885HSD17B10 2362/4885 |
| US-20200262829-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate in the Brain | MAPT, FABP7, HTT | ALDH1A1 1870/4885LMNA 3862/4885HSD17B10 225/4885 |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | MAPT, FABP7, HTT | ALDH1A1 2088/4885LMNA 3890/4885HSD17B10 246/4885 |
| US-10604516-B2 | Compounds for imaging tau proteins that accumulate in the brain | MAPT, FABP7, HTT | ALDH1A1 1701/4885LMNA 3784/4885HSD17B10 239/4885 |
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | MAPT, FABP7, HTT | ALDH1A1 1901/4885LMNA 3805/4885HSD17B10 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.