Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454999 | 1.00 | SLC6A3 (0.33) | SLC6A3HTR3ADRD2MDM2TP53 | |
| SCHEMBL5684499 | 0.93 | SLC6A3 (0.32) | SLC6A3HTR3ADRD2MDM2TP53 | |
| SCHEMBL5684503 | 0.93 | SLC6A3 (0.32) | SLC6A3HTR3ADRD2MDM2TP53 | |
| SCHEMBL6450757 | 0.87 | IDO1 (0.39) | HTR3ADRD2TP53IDO1ESR2 | |
| SCHEMBL6450760 | 0.87 | IDO1 (0.39) | HTR3ADRD2TP53IDO1ESR2 | |
| SCHEMBL6459259 | 0.86 | ESR2 (0.32) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL6457695 | 0.86 | ESR2 (0.32) | SLC6A3ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL6457691 | 0.86 | ESR2 (0.32) | SLC6A3ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL6452603 | 0.86 | ESR2 (0.32) | ESR2ESR1CYP3A4CYP2C9KDM1A | |
| SCHEMBL6452610 | 0.86 | ESR2 (0.32) | ESR2ESR1CYP3A4CYP2C9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |