Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684503 | 1.00 | SLC6A3 (0.32) | SLC6A3DRD2TP53MDM2HTR3A | |
| SCHEMBL6455002 | 0.93 | SLC6A3 (0.33) | SLC6A3DRD2TP53MDM2HTR3A | |
| SCHEMBL6454999 | 0.93 | SLC6A3 (0.33) | SLC6A3DRD2TP53MDM2HTR3A | |
| SCHEMBL5686521 | 0.87 | SLC6A2 (0.31) | SLC6A3ESR2 | |
| SCHEMBL5686524 | 0.87 | SLC6A2 (0.31) | SLC6A3ESR2 | |
| SCHEMBL5687117 | 0.85 | DRD2 (0.33) | DRD2HTR3AIDO1 | |
| SCHEMBL5687111 | 0.85 | DRD2 (0.33) | DRD2HTR3AIDO1 | |
| SCHEMBL5687496 | 0.84 | CCR2 (0.33) | — | |
| SCHEMBL5687501 | 0.84 | CCR2 (0.33) | — | |
| SCHEMBL5686983 | 0.84 | HTR2C (0.37) | IDO1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |