Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851500 | 0.83 | RAB9A (0.79) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL27193042 | 0.83 | RAB9A (0.79) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL2090934 | 0.82 | MEN1 (0.69) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL30130671 | 0.82 | MEN1 (0.69) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL2090931 | 0.82 | MEN1 (0.69) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL28638736 | 0.81 | GAA (0.73) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL167713 | 0.80 | MEN1 (0.67) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL687148 | 0.80 | GAA (0.68) | MEN1KMT2ARAB9ANPC1TSHR | |
| Hydrochloric Acid SCHEMBL11459054 | 0.80 | MEN1 (0.67) | MEN1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL2796800 | 0.80 | MEN1 (0.67) | MEN1KMT2ARAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575946-A1 | QUINAZOLINE COMPOUNDS | AstraZeneca AB (SE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004058752-A1 | QUINAZOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-07-15 | — | — | WO | disclosed |