Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 15/20 | 0.45 |
| ▸ | CA9 | Q16790 | 15/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941371 | 0.87 | KMT2A (0.47) | CA12CA9SMN1; SMN2TP53MEN1 | |
| SCHEMBL3454762 | 0.86 | CA12 (0.55) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL31465210 | 0.84 | CA9 (0.45) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL31465208 | 0.83 | TP53 (0.65) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL30076512 | 0.80 | CA12 (0.52) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL2997436 | 0.78 | ALDH1A1 (0.47) | CA9CA2SMN1; SMN2CA1LMNA | |
| SCHEMBL4167677 | 0.78 | CA12 (0.42) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL17688820 | 0.77 | CA9 (0.43) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL11411674 | 0.76 | CA12 (0.45) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL365842 | 0.76 | TSHR (0.47) | CA12CA9CA2SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | CA12 4770/4885CA9 4851/4885CA2 4346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.