Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455888 | 1.00 | RIPK1 (0.32) | RIPK1SLC6A2SLC6A4SLC6A3TRPA1 | |
| SCHEMBL6456214 | 0.87 | HTR2A (0.35) | — | |
| SCHEMBL6456219 | 0.87 | HTR2A (0.35) | — | |
| SCHEMBL6461349 | 0.86 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6461351 | 0.86 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9311759 | 0.86 | SLC6A2 (0.35) | RIPK1SLC6A2SLC6A4SLC6A3HTR7 | |
| SCHEMBL8972154 | 0.86 | SLC6A2 (0.35) | RIPK1SLC6A2SLC6A4SLC6A3HTR7 | |
| SCHEMBL6454020 | 0.85 | — | — | |
| SCHEMBL6454023 | 0.85 | — | — | |
| SCHEMBL6458821 | 0.84 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |