Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455978 | 1.00 | CTSK (0.39) | CTSKNAAAEPHX2PDE2AGRIN1 | |
| SCHEMBL6451944 | 0.92 | CTSK (0.38) | CTSKNAAAEPHX2PDE2AGRM2 | |
| SCHEMBL6451948 | 0.92 | CTSK (0.38) | CTSKNAAAEPHX2PDE2AGRM2 | |
| SCHEMBL6452906 | 0.91 | GRIN1 (0.32) | CTSKNAAAGRIN1GRIN2BKDM1A | |
| SCHEMBL6452912 | 0.91 | GRIN1 (0.32) | CTSKNAAAGRIN1GRIN2BKDM1A | |
| SCHEMBL6455580 | 0.90 | CTSK (0.37) | CTSKNAAAEPHX2PDE2AGRM2 | |
| SCHEMBL6452975 | 0.90 | CTSK (0.37) | CTSKNAAAEPHX2PDE2AGRM2 | |
| SCHEMBL6452981 | 0.90 | CTSK (0.37) | CTSKNAAAEPHX2PDE2AGRM2 | |
| SCHEMBL6455576 | 0.90 | CTSK (0.37) | CTSKNAAAEPHX2PDE2AGRM2 | |
| SCHEMBL6455741 | 0.89 | CTSK (0.36) | CTSKNAAAEPHX2PDE2AGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |