Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456054 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRHSD17B10TLR9 | |
| SCHEMBL6458470 | 0.87 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRHSD17B10TLR9 | |
| SCHEMBL6458467 | 0.87 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRHSD17B10TLR9 | |
| SCHEMBL6459897 | 0.87 | SCN9A (0.33) | ALDH1A1HPGDTSHRHSD17B10TLR9 | |
| SCHEMBL6459901 | 0.87 | SCN9A (0.33) | ALDH1A1HPGDTSHRHSD17B10TLR9 | |
| SCHEMBL6453004 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TLR9TLR8SLC6A3SLC6A4 | |
| SCHEMBL6453013 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TLR9TLR8SLC6A3SLC6A4 | |
| SCHEMBL6459928 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HPGDTSHRHSD17B10SLC6A3 | |
| SCHEMBL6459924 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HPGDTSHRHSD17B10SLC6A3 | |
| SCHEMBL6455749 | 0.83 | MAOA (0.33) | ALDH1A1TLR9TLR8SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |