Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456094 | 1.00 | CYP2C9 (0.43) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL11031253 | 1.00 | CYP2C9 (0.43) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL6451911 | 0.91 | DRD2 (0.40) | CYP2C9DRD2MAPTMEN1MAPK1 | |
| SCHEMBL11029706 | 0.91 | DRD2 (0.40) | CYP2C9DRD2MAPTMEN1MAPK1 | |
| SCHEMBL6451908 | 0.91 | DRD2 (0.40) | CYP2C9DRD2MAPTMEN1MAPK1 | |
| SCHEMBL2829069 | 0.90 | DRD2 (0.47) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL6453957 | 0.89 | CFTR (0.39) | DRD2 | |
| SCHEMBL11030592 | 0.89 | CFTR (0.39) | DRD2 | |
| SCHEMBL6453962 | 0.89 | CFTR (0.39) | DRD2 | |
| SCHEMBL6456109 | 0.89 | CFTR (0.39) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |