Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441572 | 0.99 | ALDH1A1 (0.35) | ALDH1A1TBXA2RLMNATSHRNFKB1 | |
| Octanedioate SCHEMBL29452953 | 0.94 | ALDH1A1 (0.35) | ALDH1A1TBXA2RLMNATSHRNFKB1 | |
| SCHEMBL8818958 | 0.94 | FABP4 (0.32) | ALDH1A1TBXA2RMEN1GAAKMT2A | |
| SCHEMBL29281340 | 0.84 | — | — | |
| SCHEMBL557138 | 0.80 | TSHR (0.40) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL1943663 | 0.80 | TSHR (0.40) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL8744936 | 0.79 | — | — | |
| SCHEMBL859389 | 0.79 | — | — | |
| SCHEMBL9008981 | 0.79 | — | — | |
| SCHEMBL8818609 | 0.76 | TSHR (0.39) | ALDH1A1LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545616-A1 | USE OF PROTEIN TYROSINE PHOSPHATASE INHIBITORS FOR PREVENTION AND/OR TREATMENT OF CANCER | Applied Research Systems ARS Holding N.V. (AN) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004030697-A1 | USE OF PROTEIN TYROSINE PHOSPHATASE INHIBITORS FOR PREVENTION AND/OR TREATMENT OF CANCER | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2004-04-15 | — | — | WO | disclosed |
| EP-0814850-A1 | CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING | Redcell Canada Inc. (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997025074-A2 | CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING | REDCELL CANADA, INC. (CA) | 1997-07-17 | — | — | WO | disclosed |