Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177685 | 0.87 | CCNB2 (0.68) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30939928 | 0.87 | CCNB2 (0.68) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL647417 | 0.86 | CCNB2 (0.66) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2730361 | 0.84 | MAOA (0.55) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL970432 | 0.84 | CCNB2 (0.64) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3769079 | 0.84 | CCNB2 (0.64) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12068041 | 0.82 | CCNB2 (0.60) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23552871 | 0.81 | HTR2C (0.51) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29227284 | 0.81 | MAOA (0.61) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5268682 | 0.81 | MAOA (0.61) | MAOAKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127013-A1 | HIGHLY EFFICIENT MYELOPEROXIDASE ACTIVATABLE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2005092359-A1 | EXTRACT OF MUCUNA SPECIES AND THE USE THEREOF AS ANTI-PARKINSONS’S DISEASE PHARMACEUTICAL | SCOTT & WHITE MEMORIAL HOSPITAL (US) | 2005-10-06 | — | — | WO | disclosed |
| US-20050202111-A1 | Anti-Parkinson's disease pharmaceutical and method of use | MANYAM BALA V (US) | 2005-09-15 | — | — | US | disclosed |