SCHEMBL177685

SCHEMBL177685

Cc1nccc2c1[nH]c1cc(O)ccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 2/20 0.68
CDK1 P06493 2/20 0.68
CCNB1 P14635 2/20 0.68
CCNA2 P20248 2/20 0.68
CDK2 P24941 2/20 0.68
CCNA1 P78396 2/20 0.68
CDK5 Q00535 2/20 0.68
CDK5R1 Q15078 2/20 0.68
CCNB3 Q8WWL7 2/20 0.68
MAOA P21397 16/20 0.67
DYRK1A Q13627 7/20 0.67
KDM4E B2RXH2 2/20 0.64
ALDH1A1 P00352 2/20 0.64
CYP1A2 P05177 2/20 0.64
CYP3A4 P08684 2/20 0.64
CYP2D6 P10635 2/20 0.64
HPGD P15428 2/20 0.64
HSD17B10 Q99714 2/20 0.64
DYRK3 O43781 1/20 0.64
CCNT1 O60563 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30939928 1.00 CCNB2 (0.68) CCNB2CDK1CCNB1CCNA2CDK2
Hydrochloric Acid SCHEMBL647417 0.98 CCNB2 (0.66) CCNB2CDK1CCNB1CCNA2CDK2
Hydrochloric Acid SCHEMBL3769079 0.97 CCNB2 (0.64) CCNB2CDK1CCNB1CCNA2CDK2
Hydrochloric Acid SCHEMBL970432 0.97 CCNB2 (0.64) CCNB2CDK1CCNB1CCNA2CDK2
Acetamide SCHEMBL28491482 0.92 DYRK1A (0.64) CCNB2CDK1CCNB1CCNA2CDK2
Propionamide SCHEMBL28500673 0.88 DYRK1A (0.60) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL6456554 0.87 MAOA (0.61) CCNB2CDK1CCNB1CCNA2CDK2
Butyramide SCHEMBL28501063 0.86 DYRK1A (0.57) CCNB2CDK1CCNB1CCNA2CDK2
Norharmane SCHEMBL1626892 0.85 MAOA (0.63) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL15236149 0.83 CCNB2 (0.71) CCNB2CDK1CCNB1CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137652-A1 Composition Comprising Non-Phosphorylated Tryptamine SINTALICA S R L (IT) 2026-05-21 US claimed
US-20260091047-A1 THERAPEUTIC COMBINATIONS FOR MOVEMENT DISORDERS NATIVE CODE BIO LLC (US) 2026-04-02 US claimed
EP-4638419-A1 NON-HALLUCINOGENIC TRYPTAMINE COMPOUNDS, PREPARATION, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Sintalica S.r.l. (IT) 2025-10-29 EP claimed
EP-4601627-A1 COMPOSITION COMPRISING NOT PHOSPHORYLATED TRYPTAMINE, ANTIOXIDANTS, AND SUPPLEMENTS, AND PHARMACEUTICAL USES THEREOF Sintalica S.r.l. (IT) 2025-08-20 EP claimed
EP-4601655-A1 DELIVERY SYSTEM FOR THE CONTROLLED RELEASE OF PSYCHEDELIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USES THEREOF Sintalica S.r.l. (IT) 2025-08-20 EP claimed
EP-4601665-A1 COMPOSITION COMPRISING TRYPTAMINES AND MAOIS COMPOUNDS SELECTED FROM ?-CARBOLINE INHIBITORS, AND PHARMACEUTICAL USES THEREOF Sintalica S.r.l. (IT) 2025-08-20 EP claimed
EP-4583856-A2 THERAPEUTIC COMBINATIONS FOR MOVEMENT DISORDERS Native Code Bio, LLC (US) 2025-07-16 EP claimed
US-20250151728-A1 ANTIMICROBIAL SYSTEM WITH BETA CARBOLINE ALKALOID AND INDOLE ALKALOID AND COMPOSITIONS COMPRISING THEM CONOPCO, INC., D/B/A UNILEVER (US) 2025-05-15 US claimed
US-20250099357-A1 ANTIMICROBIAL SYSTEM WITH BETA CARBOLINE ALKALOID AND PHENOLIC ACID AND COMPOSITIONS COMPRISING THEM CONOPCO, INC., D/B/A UNILEVER (US) 2025-03-27 US claimed
WO-2024254645-A1 COMPOSITION AND METHOD TO TREAT, AMELIORATE OR PREVENT A PSYCHOLOGICAL, NEUROLOGICAL OR INFLAMMATORY DISORDER, AND METHOD FOR PREPARING COMPOSITION Psychae Therapeutics Pty Ltd (AU) 2024-12-19 WO claimed
WO-2008112195-A1 METHODS FOR IDENTIFYING AGENTS AND THEIR USE FOR THE PREVENTION OR STABILIZATION OF FIBROSIS BIOSEEK, INC. (US) 2008-09-18 WO claimed
WO-2006124003-A1 COMPOSITE MALDI MATRIX MATERIAL AND METHODS OF USING IT AND KITS THEREOF IN MALDI AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-11-23 WO claimed
US-20060261267-A1 Composite MALDI matrix material and methods of using it and kits thereof in MALDI AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2006-11-23 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-0620918-B1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL (GB) 1997-07-30 EP claimed
US-5591738-A Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof NDA INTERNATIONAL, INC. (US) 1997-01-07 US claimed
US-5480611-A Carbon dioxide detector GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC. 1996-01-02 US claimed
EP-0620918-A1 CARBON DIOXIDE DETECTOR. JOHNSON & JOHNSON PROFESSIONAL (GB) 1994-10-26 EP claimed
WO-1993014399-A1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL PRODUCTS LTD. (GB) 1993-07-22 WO claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099357-A1 ANTIMICROBIAL SYSTEM WITH BETA CARBOLINE ALKALOID AND PHENOLIC ACID AND COMPOSITIONS COMPRISING THEM DBH, CGAS, MAVS CCNB2 2050/4885CDK1 2736/4885CCNB1 2432/4885
US-20260091047-A1 THERAPEUTIC COMBINATIONS FOR MOVEMENT DISORDERS HMBS, SNCA, PYGB CCNB2 1542/4885CDK1 1668/4885CCNB1 929/4885
US-20250151728-A1 ANTIMICROBIAL SYSTEM WITH BETA CARBOLINE ALKALOID AND INDOLE ALKALOID AND COMPOSITIONS COMPRISING THEM IDO1, IDO2, MAVS CCNB2 2370/4885CDK1 3006/4885CCNB1 2648/4885
US-20260137652-A1 Composition Comprising Non-Phosphorylated Tryptamine HTR2B, BDNF, HTR3B CCNB2 593/4885CDK1 270/4885CCNB1 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.