Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457049 | 1.00 | KIF11 (0.46) | KIF11PGRCXCR2LMNAALDH1A1 | |
| SCHEMBL688271 | 0.87 | PPARG (0.46) | CXCR2LMNAPPARGPTPN1CXCR1 | |
| SCHEMBL688272 | 0.87 | PPARG (0.46) | CXCR2LMNAPPARGPTPN1CXCR1 | |
| SCHEMBL687781 | 0.85 | PPARG (0.45) | CXCR2LMNAPPARGPTPN1CXCR1 | |
| SCHEMBL687782 | 0.85 | PPARG (0.45) | CXCR2LMNAPPARGPTPN1CXCR1 | |
| SCHEMBL688839 | 0.84 | ALDH1A1 (0.47) | KIF11PGRLMNAALDH1A1HPGD | |
| SCHEMBL688840 | 0.84 | ALDH1A1 (0.47) | KIF11PGRLMNAALDH1A1HPGD | |
| SCHEMBL10253658 | 0.84 | KIF11 (0.61) | KIF11PGRCXCR2LMNAALDH1A1 | |
| SCHEMBL688506 | 0.82 | CA12 (0.49) | KIF11LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL688504 | 0.82 | ALDH1A1 (0.46) | KIF11PGRLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.P.A. (IT) | 2005-12-21 | — | — | EP | claimed |
| WO-2004080951-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A. (IT) | 2004-09-23 | — | — | WO | claimed |