Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457381 | 1.00 | DRD2 (0.42) | DRD2SLC6A2SLC6A4SLC6A3RAB9A | |
| SCHEMBL6457374 | 1.00 | DRD2 (0.42) | DRD2SLC6A2SLC6A4SLC6A3RAB9A | |
| SCHEMBL6463205 | 0.86 | IDO1 (0.37) | RAB9ASMN1; SMN2 | |
| SCHEMBL6457862 | 0.86 | KDM1A (0.37) | DRD2SLC6A4SLC6A3RAB9AKDM1A | |
| SCHEMBL6463200 | 0.86 | IDO1 (0.37) | RAB9ASMN1; SMN2 | |
| SCHEMBL6457876 | 0.86 | KDM1A (0.37) | DRD2SLC6A4SLC6A3RAB9AKDM1A | |
| SCHEMBL6463207 | 0.86 | IDO1 (0.37) | RAB9ASMN1; SMN2 | |
| SCHEMBL6457866 | 0.86 | KDM1A (0.37) | DRD2SLC6A4SLC6A3RAB9AKDM1A | |
| SCHEMBL6460336 | 0.85 | DRD2 (0.40) | DRD2SLC6A3 | |
| SCHEMBL6453979 | 0.85 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |