Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457866 | 1.00 | KDM1A (0.37) | KDM1ARCOR1HRH3L3MBTL1EPHX2 | |
| SCHEMBL6457862 | 1.00 | KDM1A (0.37) | KDM1ARCOR1HRH3L3MBTL1EPHX2 | |
| SCHEMBL5686775 | 0.95 | KDM1A (0.35) | KDM1ARCOR1HRH3L3MBTL1EPHX2 | |
| SCHEMBL5686770 | 0.95 | KDM1A (0.35) | KDM1ARCOR1HRH3L3MBTL1EPHX2 | |
| SCHEMBL6457374 | 0.86 | DRD2 (0.42) | KDM1ARAB9ADRD2SLC6A4SLC6A3 | |
| SCHEMBL6457381 | 0.86 | DRD2 (0.42) | KDM1ARAB9ADRD2SLC6A4SLC6A3 | |
| SCHEMBL6457368 | 0.86 | DRD2 (0.42) | KDM1ARAB9ADRD2SLC6A4SLC6A3 | |
| SCHEMBL5684721 | 0.85 | KDM1A (0.36) | KDM1ARCOR1HRH3L3MBTL1EPHX2 | |
| SCHEMBL5684725 | 0.85 | KDM1A (0.36) | KDM1ARCOR1HRH3L3MBTL1EPHX2 | |
| SCHEMBL6464028 | 0.84 | HRH3 (0.37) | KDM1ARCOR1HRH3L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |