Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708161 | 0.90 | CYP1A2 (0.56) | TDP1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL9595497 | 0.89 | TDP1 (0.56) | TDP1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL28921963 | 0.88 | CYP1A2 (0.54) | TDP1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL6409790 | 0.87 | TDP1 (0.54) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8743473 | 0.87 | TDP1 (0.54) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL20425405 | 0.87 | MAPT (0.51) | TDP1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL9446561 | 0.85 | MAPT (0.74) | TDP1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL27765388 | 0.85 | MAPT (0.57) | TDP1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL5841958 | 0.85 | TDP1 (0.53) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1678635 | 0.85 | L3MBTL1 (0.55) | TDP1MAPTKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318052-B2 | Diketopyrrolopyrrole cocrystals with high transparency | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-11-27 | — | — | US | disclosed |
| US-8119042-B2 | Diketopyrrolopyrrole cocrystals | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-02-21 | — | — | US | disclosed |
| US-20100213421-A1 | Diketopyrrolopyrrole Cocrystals | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-08-26 | — | — | US | disclosed |
| US-20100119966-A1 | Diketopyrrolopyrrole Cocrystals With High Transparency | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-05-13 | — | — | US | disclosed |
| US-5492564-A | HIGH OPACITY, COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119966-A1 | Diketopyrrolopyrrole Cocrystals With High Transparency | TYR, DYRK1A, TP53RK | TDP1 1019/4885MAPT 678/4885KMT2A 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.