SCHEMBL6409790

SCHEMBL6409790

O=C(CO)Oc1ccc(Cl)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
PPARA Q07869 1/20 0.51
KMT2A Q03164 3/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 1/20 0.49
TSHR P16473 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
HPGD P15428 2/20 0.48
GAA P10253 1/20 0.48
ALOX12 P18054 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.46
NR1I2 O75469 1/20 0.46
LMNA P02545 1/20 0.46
TTR P02766 1/20 0.46
PGR P06401 1/20 0.46
HSP90AA1 P07900 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2118037 0.89 TTR (0.51) TDP1PPARAMAPTALDH1A1L3MBTL1
SCHEMBL9595497 0.87 TDP1 (0.56) TDP1PPARAKMT2AMAPTALDH1A1
SCHEMBL645781 0.87 TDP1 (0.56) TDP1PPARAKMT2AMAPTALDH1A1
SCHEMBL8743473 0.85 TDP1 (0.54) TDP1PPARAKMT2AMAPTALDH1A1
SCHEMBL5841958 0.84 TDP1 (0.53) TDP1PPARAKMT2AMAPTALDH1A1
SCHEMBL1678635 0.84 L3MBTL1 (0.55) TDP1KMT2AMAPTALDH1A1MEN1
SCHEMBL9799896 0.84 L3MBTL1 (0.55) TDP1KMT2AMAPTALDH1A1MEN1
SCHEMBL9159636 0.84 TDP1 (0.53) TDP1PPARAKMT2AMAPTALDH1A1
SCHEMBL10878098 0.84 TDP1 (0.53) TDP1PPARAKMT2AMAPTALDH1A1
SCHEMBL9595502 0.82 TDP1 (0.60) TDP1PPARAKMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed
US-20050272606-A1 Plant life control composition MANCHAK FRANK JR 2005-12-08 US disclosed
WO-2001035746-A1 PLANT LIFE CONTROL COMPOSITION ATW INCORPORATED (US) 2001-05-25 WO disclosed
EP-0231765-A1 Use of membrane modulators and products comprising such membrane modulators A. Nattermann & Cie. GmbH (DE) 1987-08-12 EP disclosed