Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460085 | 0.82 | KMT2A (0.40) | LMNAKMT2AMEN1RAB9ASLC6A2 | |
| SCHEMBL17295886 | 0.80 | CES2 (0.41) | LMNAKMT2AMEN1RAB9ASLC6A2 | |
| SCHEMBL8067277 | 0.69 | KMT2A (0.45) | LMNAKDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL50648 | 0.69 | KMT2A (0.56) | LMNAL3MBTL1KMT2AMEN1NPSR1 | |
| SCHEMBL2722492 | 0.69 | KMT2A (0.39) | LMNAKMT2AMEN1RAB9ASLC6A2 | |
| Bicarbonate SCHEMBL15643478 | 0.67 | KMT2A (0.54) | LMNAL3MBTL1KMT2AMEN1NPSR1 | |
| Lithium SCHEMBL30994890 | 0.67 | KMT2A (0.54) | LMNAL3MBTL1KMT2AMEN1NPSR1 | |
| Benzophenone SCHEMBL3324674 | 0.67 | ALDH1A1 (0.58) | LMNAL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL31220878 | 0.67 | KMT2A (0.54) | LMNAL3MBTL1KMT2AMEN1NPSR1 | |
| SCHEMBL28867988 | 0.67 | KMT2A (0.54) | LMNAL3MBTL1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900280-B2 | Acid macromonomers and their method of preparation | CIBA SPECIALTY CHEMICALS CORP. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040072978-A1 | Compositions of acid macromonomers and their method of preparation | CIBA SPECIALTY CHEMICALS CORP. | 2004-04-15 | — | — | US | disclosed |
| EP-1392736-A2 | ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION | Ciba SC Holding AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-6576684-B1 | Ammonium, phosphonium or sulfonium containing oligomers or polymers; controlled molecular weight, low polydispersity and a vinyl or dienyl end group; polymeric precursors and addi-tives | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-10 | — | — | US | disclosed |
| US-6489374-B1 | ORGANONITROGEN COMPOUNDS THAT YIELD AMINES, IMINES OR AMIDINES WHEN EXPOSED TO VISIBLE OR ULTRAVIOLET RADIATION; POLYMERIZATION CATALYSTS USED IN ONE-POT SYSTEMS HAVING STORAGE STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-12-03 | — | — | US | disclosed |
| WO-2002079271-A2 | ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |