Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458139 | 1.00 | MAPT (0.34) | MAPTGRIN1GRIN2BPPARDPPARA | |
| SCHEMBL6457292 | 0.91 | TTR (0.38) | MAPTGRIN1GRIN2BTDP1RAB9A | |
| SCHEMBL6457287 | 0.91 | TTR (0.38) | MAPTGRIN1GRIN2BTDP1RAB9A | |
| SCHEMBL6455921 | 0.90 | TDP1 (0.41) | MAPTGRIN1GRIN2BGAATDP1 | |
| SCHEMBL6452092 | 0.90 | ALDH1A1 (0.40) | MAPTGAATDP1ALDH1A1PRSS1 | |
| SCHEMBL6452087 | 0.90 | ALDH1A1 (0.40) | MAPTGAATDP1ALDH1A1PRSS1 | |
| SCHEMBL6455915 | 0.90 | TDP1 (0.41) | MAPTGRIN1GRIN2BGAATDP1 | |
| SCHEMBL6454830 | 0.89 | SCN9A (0.33) | MAPTPPARDPPARAGAATP53 | |
| SCHEMBL6454828 | 0.89 | SCN9A (0.33) | MAPTPPARDPPARAGAATP53 | |
| SCHEMBL6464036 | 0.89 | TRPV1 (0.41) | MAPTGAATDP1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |