Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 5/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458563 | 1.00 | FFAR4 (0.35) | FFAR4TRPV1HRH3EPHX2PDE2A | |
| SCHEMBL6459501 | 0.87 | ALDH1A1 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6459496 | 0.87 | ALDH1A1 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6455509 | 0.86 | FFAR4 (0.34) | FFAR4TRPV1PDE2ASLC6A2SLC6A4 | |
| SCHEMBL6455510 | 0.86 | FFAR4 (0.34) | FFAR4TRPV1PDE2ASLC6A2SLC6A4 | |
| SCHEMBL6460298 | 0.86 | SLC6A2 (0.38) | FFAR4TRPV1HRH3EPHX2IDH1 | |
| SCHEMBL6460293 | 0.86 | SLC6A2 (0.38) | FFAR4TRPV1HRH3EPHX2IDH1 | |
| SCHEMBL6454287 | 0.84 | FFAR4 (0.33) | FFAR4TRPV1EPHX2 | |
| SCHEMBL6454289 | 0.84 | FFAR4 (0.33) | FFAR4TRPV1EPHX2 | |
| SCHEMBL6462671 | 0.83 | HCRTR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |