Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460298 | 1.00 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3TRPV1HRH3 | |
| SCHEMBL6458563 | 0.86 | FFAR4 (0.35) | SLC6A2SLC6A4SLC6A3TRPV1HRH3 | |
| SCHEMBL6458557 | 0.86 | FFAR4 (0.35) | SLC6A2SLC6A4SLC6A3TRPV1HRH3 | |
| SCHEMBL6460474 | 0.85 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL6460483 | 0.85 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL6452713 | 0.84 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3HRH3KDM1A | |
| SCHEMBL6452710 | 0.84 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3HRH3KDM1A | |
| SCHEMBL6454321 | 0.84 | L3MBTL1 (0.43) | HRH3EPHX2KDM1ARCOR1L3MBTL1 | |
| SCHEMBL6454317 | 0.84 | L3MBTL1 (0.43) | HRH3EPHX2KDM1ARCOR1L3MBTL1 | |
| SCHEMBL6461538 | 0.84 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3TRPV1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |