SCHEMBL16892913

SCHEMBL16892913

Cc1ccc(C2CCC(C)C2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.50
LMNA P02545 2/20 0.41
SLC18A3 Q16572 1/20 0.39
MAPT P10636 2/20 0.38
ATM Q13315 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
PKM P14618 1/20 0.36
MAP1LC3B Q9GZQ8 1/20 0.36
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21568471 0.88 ALDH1A1 (0.41) ESR2LMNASLC18A3MAPTATM
SCHEMBL19937427 0.86 ESR2 (0.65) ESR2LMNASLC18A3MAPTATM
SCHEMBL24597681 0.86 ESR2 (0.65) ESR2LMNASLC18A3MAPTATM
SCHEMBL6458694 0.84 ESR2 (0.41) ESR2LMNASLC18A3MAPTATM
SCHEMBL6458692 0.84 ESR2 (0.41) ESR2LMNASLC18A3MAPTATM
SCHEMBL21741409 0.83 ESR2 (0.38) ESR2LMNASLC18A3MAPTHRH3
SCHEMBL1405569 0.81 ESR2 (0.50) ESR2LMNASLC18A3MAPTATM
SCHEMBL21503504 0.81 ESR2 (0.48) ESR2HRH3HTR2AHTR2CHTR2B
SCHEMBL11156732 0.81 ESR2 (0.77) ESR2CYP3A4CYP2C9CYP2D6
SCHEMBL23368935 0.81 ESR2 (0.48) ESR2LMNAHTR2CHTR2BCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111727516-B Sealing body and battery FDK株式会社 2023-12-05 CN disclosed
CN-114207756-B Hybrid capacitor 帝伯爱尔株式会社 2023-06-09 CN disclosed
CN-114207756-A Hybrid capacitor 帝伯爱尔株式会社 2022-03-18 CN disclosed
CN-111727516-A Sealing body and battery FDK株式会社 2020-09-29 CN disclosed
EP-2174980-B2 High flowable heterophasic polypropylene BOREALIS AG (AT) 2018-10-24 EP disclosed
EP-2027081-B1 THERAPEUTIC PROSTAGLANDIN COMPOUNDS FOR THE TREATMENT OF GLAUCOMA ALLERGAN INC (US) 2017-05-03 EP disclosed
EP-2174980-B1 High flowable heterophasic polypropylene BOREALIS AG (AT) 2015-07-15 EP disclosed