Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29779666 | 1.00 | NOS2 (0.50) | NOS2UHRF1CCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL28783127 | 0.98 | NOS2 (0.49) | NOS2UHRF1CCR1CCR5CCR8 | |
| Iodide SCHEMBL29869193 | 0.98 | NOS2 (0.49) | NOS2UHRF1CCR1CCR5CCR8 | |
| Phosphine SCHEMBL27841866 | 0.98 | NOS2 (0.49) | NOS2UHRF1CCR1CCR5CCR8 | |
| SCHEMBL1030077 | 0.94 | KDM4E (0.47) | NOS2UHRF1CCR1CCR5CCR8 | |
| SCHEMBL921653 | 0.94 | KDM4E (0.47) | NOS2UHRF1CCR1CCR5CCR8 | |
| SCHEMBL29473921 | 0.94 | KDM4E (0.47) | NOS2UHRF1CCR1CCR5CCR8 | |
| SCHEMBL28096091 | 0.93 | NOS2 (0.45) | NOS2UHRF1CCR1CCR5CCR8 | |
| SCHEMBL2547957 | 0.92 | KCNH2 (0.48) | NOS2UHRF1CCR1CCR5CCR8 | |
| SCHEMBL28878273 | 0.92 | KCNH2 (0.48) | NOS2UHRF1CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153189-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | Merck Sharp & Dohme LLC (US) | 2023-03-29 | — | — | EP | claimed |
| WO-2021236859-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2021-11-25 | — | — | WO | claimed |
| CN-104411688-B | Synthesis of acridinium compounds from N-alkylation of 9,10-dihydroacridine | 西门子医疗保健诊断公司 | 2019-01-08 | — | — | CN | claimed |
| CN-107427758-A | Utilize the separation of ion liquid solvent | 切弗朗菲利浦化学公司 | 2017-12-01 | — | — | CN | claimed |
| CN-104411688-A | Synthesis of acridinium compounds from N-alkylation of 9, 10-dihydroacridine | SIEMENS HEALTHCARE DIAGNOSTICS | 2015-03-11 | — | — | CN | claimed |
| CN-1705639-A | Synthesis of intermediates useful in the synthesis of tubulin inhibitors | WYETH CORP (US) | 2005-12-07 | — | — | CN | claimed |
| US-20230357286-A1 | KETONE SYNTHESIS AND APPLICATIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | disclosed |
| CN-116092839-A | Super capacitor with wide temperature range | 快帽系统公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115947767-A | Method for synthesizing 1,3-dithio glycoside by one-pot relay glycosylation | 江西师范大学 | 2023-04-11 | — | — | CN | disclosed |
| EP-4153189-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | Merck Sharp & Dohme LLC (US) | 2023-03-29 | — | — | EP | disclosed |
| WO-2021067606-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| CN-110526898-A | 3- indazole quinoline ketone compounds, preparation method and its in application pharmaceutically | BEIJING INNOCARE PHARMA TECH CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-1144217-A | Retinoid-like compounds | BRISTOL MYERS SQUIBB CO (US) | 1997-03-05 | — | — | CN | disclosed |
| WO-1996005216-A1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JENAPHARM GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |
| CN-1095382-A | The new A of cyanines family ring steroide | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | CN | disclosed |
| CN-1095071-A | The acyl group that 17 α and 17 β replace-3-carboxyl fragrance A ring steroide 5-alpha-reductase inhibitors | SMITHKLINE BEECHAM CORP (US) | 1994-11-16 | — | — | CN | disclosed |
| CN-1087902-A | Morpholine and thiomorpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 1994-06-15 | — | — | CN | disclosed |
| WO-1994003164-A1 | INHIBITION AND TREATMENT OF INFECTION BY ENVELOPED VIRUS WITH CALIX(N) ARENE COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| CN-1048546-A | Substituted imidazo-fused 6 unit heterocycle as angiotensin II antagonism medicine | MERCK & CO INC (US) | 1991-01-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | EGFR, ERBB2, ERBB4 | NOS2 2587/4885UHRF1 3037/4885CCR1 2558/4885 |
| US-20230357286-A1 | KETONE SYNTHESIS AND APPLICATIONS | NISCH, COASY, KLK7 | NOS2 3449/4885UHRF1 2298/4885CCR1 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.