Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030077 | 1.00 | KDM4E (0.47) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL29473921 | 1.00 | KDM4E (0.47) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL28183218 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL27876575 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL27655489 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL2547957 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL28142250 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL28878273 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL2551597 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 | |
| SCHEMBL28142976 | 0.98 | KCNH2 (0.48) | KDM4EKCNH2HPGDNOS2UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4628168-A2 | DENSITY BALANCED HIGH IMPACT PERFUME MICROCAPSULES | Firmenich SA (CH) | 2025-10-08 | — | — | EP | claimed |
| EP-4608360-A1 | ANTI-DANDRUFF COMPOSITIONS | Firmenich SA (CH) | 2025-09-03 | — | — | EP | claimed |
| EP-3559193-B1 | DENSITY BALANCED HIGH IMPACT PERFUME MICROCAPSULES | FIRMENICH & CIE (CH) | 2025-07-30 | — | — | EP | claimed |
| US-20240390544-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2024-11-28 | — | — | US | claimed |
| US-12048783-B2 | 2,4-disubstituted pyridines as malodor counteracting ingredients | FIRMENICH SA (CH) | 2024-07-30 | — | — | US | claimed |
| WO-2024133645-A1 | ANTI-DANDRUFF COMPOSITIONS | FIRMENICH SA (CH) | 2024-06-27 | — | — | WO | claimed |
| EP-3648763-B1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH & CIE (CH) | 2022-11-30 | — | — | EP | claimed |
| CN-110099993-B | High impact perfume microcapsules of balanced density | 弗门尼舍有限公司 | 2021-08-24 | — | — | CN | claimed |
| US-20210145998-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2021-05-20 | — | — | US | claimed |
| US-10918579-B2 | Density balanced high impact perfume microcapsules | FIRMENICH SA (CH) | 2021-02-16 | — | — | US | claimed |
| WO-2019008089-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2019-01-10 | — | — | WO | claimed |
| WO-2018115250-A1 | DENSITY BALANCED HIGH IMPACT PERFUME MICROCAPSULES | FIRMENICH SA (CH) | 2018-06-28 | — | — | WO | claimed |
| WO-2018050655-A1 | PERFUMING COMPOSITION | FIRMENICH SA (CH) | 2018-03-22 | — | — | WO | claimed |
| WO-2018050658-A1 | PERFUMING COMPOSITION | FIRMENICH SA (CH) | 2018-03-22 | — | — | WO | claimed |
| CN-102802600-B | As 2,4-disubstituted pyridines of perfuming component | FIRMENICH S.A. (CH) | 2016-04-13 | — | — | CN | claimed |
| US-8652452-B2 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH SA (CH) | 2014-02-18 | — | — | US | claimed |
| EP-2552395-B1 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH & CIE (CH) | 2013-11-13 | — | — | EP | claimed |
| EP-2552395-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2013-02-06 | — | — | EP | claimed |
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2013-01-03 | — | — | US | claimed |
| WO-2011121469-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2011-10-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | P2RX5, P2RX4, C5 | KDM4E 2458/4885KCNH2 184/4885HPGD 244/4885 |
| US-20210145998-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | TAS2R4, P2RY4, QDPR | KDM4E 947/4885KCNH2 556/4885HPGD 437/4885 |
| US-12048783-B2 | 2,4-disubstituted pyridines as malodor counteracting ingredients | TAS2R4, P2RY4, QDPR | KDM4E 947/4885KCNH2 556/4885HPGD 437/4885 |
| US-20240390544-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | TAS2R4, LPO, PRDX4 | KDM4E 1768/4885KCNH2 979/4885HPGD 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.