Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | TP53 | P04637 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450307 | 0.88 | S1PR1 (0.51) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6452479 | 0.86 | S1PR1 (0.52) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6449738 | 0.81 | NPC1 (0.64) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6451277 | 0.81 | SMN1; SMN2 (0.50) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6457047 | 0.81 | S1PR1 (0.58) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6454839 | 0.80 | S1PR1 (0.52) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6451282 | 0.79 | NPC1 (0.74) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6448845 | 0.76 | KDM4E (0.65) | S1PR1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7007771 | 0.74 | SCN9A (0.46) | L3MBTL1MAPK1RECQLLMNA | |
| SCHEMBL6450069 | 0.74 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9ATP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | S1PR1 3213/4885SMN1; SMN2 4633/4885NPC1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.