Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459504 | 1.00 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4PTGS2PTGS1 | |
| SCHEMBL14526178 | 0.95 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4ADRB2ALDH1A1 | |
| SCHEMBL6451032 | 0.90 | SLC6A4 (0.37) | SLC6A3SLC6A2SLC6A4ALDH1A1CYP2C9 | |
| SCHEMBL6451028 | 0.90 | SLC6A4 (0.37) | SLC6A3SLC6A2SLC6A4ALDH1A1CYP2C9 | |
| SCHEMBL6454892 | 0.89 | CYP2C9 (0.42) | SLC6A3SLC6A2SLC6A4PTGS2PTGS1 | |
| SCHEMBL6454896 | 0.89 | CYP2C9 (0.42) | SLC6A3SLC6A2SLC6A4PTGS2PTGS1 | |
| SCHEMBL6452326 | 0.87 | SLC6A2 (0.37) | SLC6A3SLC6A2SLC6A4ADRB2CYP2C9 | |
| SCHEMBL6452319 | 0.87 | SLC6A2 (0.37) | SLC6A3SLC6A2SLC6A4ADRB2CYP2C9 | |
| SCHEMBL6458705 | 0.87 | PAX8 (0.40) | SLC6A3SLC6A2SLC6A4KDM1AHTR2C | |
| SCHEMBL6458715 | 0.87 | PAX8 (0.40) | SLC6A3SLC6A2SLC6A4KDM1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |