Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459520 | 1.00 | DRD2 (0.38) | DRD2KCNH2SLC6A3HTR3ASLC6A2 | |
| SCHEMBL6453238 | 0.92 | DRD2 (0.44) | DRD2SLC6A3HTR3ALSSIDO1 | |
| SCHEMBL6453234 | 0.92 | DRD2 (0.44) | DRD2SLC6A3HTR3ALSSIDO1 | |
| SCHEMBL6452970 | 0.90 | DRD2 (0.40) | DRD2KCNH2SLC6A3HTR3A | |
| SCHEMBL6452974 | 0.90 | DRD2 (0.40) | DRD2KCNH2SLC6A3HTR3A | |
| SCHEMBL6458080 | 0.88 | FFAR1 (0.43) | KCNH2 | |
| SCHEMBL6458086 | 0.88 | FFAR1 (0.43) | KCNH2 | |
| SCHEMBL6453160 | 0.87 | DRD2 (0.41) | DRD2SLC6A3HTR3ALSSIDO1 | |
| SCHEMBL6453157 | 0.87 | DRD2 (0.41) | DRD2SLC6A3HTR3ALSSIDO1 | |
| SCHEMBL6454214 | 0.87 | DRD2 (0.38) | DRD2KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |