Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370991 | 0.78 | SRC (0.40) | ALDH1A1LMNATSHRSRC | |
| SCHEMBL1572640 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EGMNNLMNA | |
| SCHEMBL4126232 | 0.74 | CA1 (0.39) | ALDH1A1MAPTKMT2ANPSR1TDP1 | |
| SCHEMBL4279670 | 0.71 | SRC (0.48) | ALDH1A1MAPTKDM4EGMNNLMNA | |
| SCHEMBL4139846 | 0.71 | POLB (0.38) | ALDH1A1MAPTPOLBKMT2ANPSR1 | |
| SCHEMBL27300404 | 0.69 | TSHR (0.42) | ALDH1A1LMNAHPGDTDP1SLC6A4 | |
| SCHEMBL30923543 | 0.69 | SLC6A4 (0.45) | ALDH1A1KDM4ELMNAKMT2ASLC6A4 | |
| SCHEMBL21216561 | 0.68 | CA1 (0.38) | ALDH1A1MAPTKDM4EGMNNLMNA | |
| SCHEMBL12251538 | 0.68 | RIPK1 (0.39) | ALDH1A1MAPTKDM4EGMNNLMNA | |
| SCHEMBL12492703 | 0.68 | CA1 (0.39) | ALDH1A1MAPTKDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | disclosed |