Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459800 | 1.00 | MAOA (0.34) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6453943 | 0.99 | MAOA (0.36) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6452488 | 0.99 | MAOA (0.36) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6453950 | 0.99 | MAOA (0.36) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6452493 | 0.99 | MAOA (0.36) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6455749 | 0.97 | MAOA (0.33) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6455747 | 0.97 | MAOA (0.33) | MAOAMAOBRAB9AALDH1A1LMNA | |
| SCHEMBL6453004 | 0.94 | ALDH1A1 (0.36) | MAOAMAOBALDH1A1LMNAMAPT | |
| SCHEMBL6453013 | 0.94 | ALDH1A1 (0.36) | MAOAMAOBALDH1A1LMNAMAPT | |
| SCHEMBL6459901 | 0.90 | SCN9A (0.33) | ALDH1A1MAPTSCN9ATLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |